Genital Itching, Discomfort, Introduction: Among the most common symptoms that accompany a sexually transmitted infection (STI) are itching, discomfort (particularly when urinating), and bumps that did not previously appear on the genitals. At the same time, however, these can all be symptoms of non-sexually transmitted infections. No one can diagnose themselves, nor can anyone be diagnosed over the phone or internet. Anyone experiencing any of these symptoms should make an appointment to see their healthcare provider.